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Efficiency of rifampicin in emergency treatment of severe hyperbilirubinemia : report of two cases and review of literature

Journal Volume 78 - 2015
Issue Fasc.2 - Reviews
Author(s) Kadir Ozturk, Hakan Demirci, Yusuf Serdar Sakin, Ahmet Uygun, Sait Bagci
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Gulhane School of Medicine, Department of Gastroenterology, Ankara, Turkey.

We showed in this study that rifampicin therapy is more effective than plasmapheresis and steroid treatment in diseases associated with severe hyperbilirubinemia. In our opinion, rifampicin treat- ment may suitable especially for patients with persistent hyper- bilirubinemia, and it would be appropriate to use rifampicin as a challenge therapy to patients with severe hyperbilirubinemia, but liver function tests in these patients must be monitored closely. (Acta gastroenterol. belg., 2015, 78, 256-258).

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PMID 26151703